Molds and Mycotoxins

Papers from an International Symposium

Edited by Kaye H. Kilburn, M.D. 2004

Are illnesses associated with exposures to indoor mold growth real, or the result of a conspiracy fueled by media hype and greedy lawyers?

This book is a compilation of 18 current, scientific, peer reviewed papers presented in 2003 - a veritable mountain of evidence that many mold-exposed people are indeed sick, with significant brain function impairment. The published investigations collected here are based on measurements of single patients and groups, studied systematically. Physiological functions and brain scans (single photon emission computed tomography (SPECT) and quantitative electroencephalograms) were abnormal. Mechanisms of mold damage to brain cells resemble those for Gulf War Syndrome, chemical intolerance, and exposure to chlorine, ammonia, or hydrogen sulfide ("rotten egg") gases. Clear evidence of brain impairment in several hundred people controverts questions and charges of malingering and secondary gain.

Exposures are invariably to mixtures of molds. Attempts to define exposure in terms of specific molds and toxins, or by searching for biomarkers in body fluids, are inconclusive. Often homes and other buildings are poorly designed, so that rather than "breathing" they collect moisture. Cold temperatures and air conditioning condense this moisture on indoor surfaces, between walls, and in ductwork. Molds grow opportunistically on wet paper, such as the cellulose present in drywall, on wooden studs and floors, carpets and pads, wallpaper, and other organic materials. Because much of the physiological damage suffered by victims of mold-related illnesses is irreversible, avoidance of mold is the key. Buildings must be designed to prevent mold growth.

These papers summarize the preliminary conclusions from studies of several hundred patients. Evidence is presented for severe neurobehavioral impairment, nasal sinus and lung dysfunctions, and immunological disturbance.

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